Abstract: Over the past twelve years, the 570-megapixel Dark Energy Camera (DECam), mounted on the 4-meter Blanco Telescope at the Cerro Tololo Inter-American Observatory in Chile, has imaged more than 20,000 square degrees of the sky at unprecedented depth. I will discuss several scientific highlights from the DECam imaging campaign, which include tripling the known population of Milky Way satellite galaxies, discovering stellar streams in the outer halo of the Milky Way, mapping the distribution of dark matter in the low-redshift universe, and constraining the dark energy equation of state. I will also discuss opportunities for the DECam instrument and the Blanco Telescope as we enter the era of the Vera C. Rubin Observatory’s Legacy Survey of Space and Time.